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  • Rebecca R. Lopez

Crohn's disease is a complex illness to live with. It can make you feel anxious and out of control with pain, especially when your symptoms are awful or if they start interrupting your everyday life's chores with frequent visits to the toilet.

CBD is a potent anti-inflammatory and has been shown to offer relief for people with Crohn's disease, ulcerative colitis, or other IBDs. In addition, it can help improve pain and inflammation in the intestines and reduce anxiety levels which are common symptoms.

CBD has been shown to have anti-inflammatory properties, which means it can reduce the pain you feel. It also helps with your gut microbiome and could make for a better quality of life.

There is not enough research to say how it works or the long-term effects, but early clinical trials show positive results in relieving some symptoms like pain and inflammation. Let's look at some of the top CBD brand to find the best CBD oil for Crohn's disease.

Top Reviews to Find the Best CBD Oil for Crohn’s Disease 

  1. Medterra: Ultra Broad-Spectrum CBD Oil – Top Pick
  2. Spruce CBD: Lab Grade CBD Oil – Natural Formula
  3. CBDPure: Hemp Oil – Variety of Strengths
  4. Joy Organics: CBD Tincture Collection – Wide Range of Flavors 
  5. Royal CBD: Full Spectrum CBD Oil – High Potent
  6. Gold Bee: Premium CBD Oil – 100% Vegan
  7. CBDistillery: CBD Oil Tincture – Best for Medium Strength

1: Medterra: Ultra Broad-Spectrum CBD Oil – Top Pick

Medterra: Ultra Broad-Spectrum CBD OilSpruce offers America's most refined CBD oils, made from a long-standing strain and tested for purity. The best way to experience the benefits of CBD is with its ultra broad-spectrum oils. The two potencies available are 1000 and 2000 mg, available in unflavored, citrus, and strawberry taste.

This company uses the CO2 extraction method for CBD oil products can remove THC and impurities to ensure quality. Furthermore, this product comes with a detailed third-party Certificate of Analysis that verifies the quality and potency.

Moreover, Medterra also adds MCT oil to enable the body’s natural absorption of cannabinoids and fat-soluble vitamins. You can feel relief without psychoactive effects when you use this product. These lab-verified products assure greater purity and are free from GMOs and pesticides.

A leader in cannabis-based remedies, this company offers a portfolio of highly potent CBD blends to treat pain and anxiety. It also provides effective formula without THC for those who need relief from Crohn’s disease as well.


  • 1000 and 2000 mg strengths available
  • Ultra broad-spectrum hemp extract
  • CO2 extraction method
  • US-grown hemp
  • 30 servings per container


  • Non-GMO recipe
  • 3rd party lab tested
  • Three different flavors
  • Certification of Analysis (COA) is available online
  • 10:1 CBD and cannabinoids ratio


  • Free shipping upon subscription only.
Medterra offers this affordable and effective way for several conditions, making it the best CBD oil for Crohn’s. In addition, its CO2 extraction process ensures that you get an all-natural experience.

2: Spruce CBD: Lab Grade CBD Oil – Natural Formula

Spruce CBD: Lab Grade CBD Oil 

To be a leader in the CBD industry, you have to work hard. That is why Spruce was founded by two North Carolinians committed to manufacturing US-made products and oils with high-quality ingredients for their customers’ needs.

One of the things that set Spruce apart is its family-run business structure. This CBD-rich hemp oil is sourced from organically grown Kentucky and North Carolina farms. This brand prides itself on an unmatched quality that has been in production for over two centuries.

Spruce is one of the only CBD companies to use a moonshine extraction method. The process is safe and effective, making it stand out compared to other hemp extracts on the market. Moreover, it is made with lab-tested hemp extracts and provides all of the cannabinoids.

This full-spectrum product has a refreshing taste and comes in a 30 ml bottle with 25 mg CBD per serving (750 mg total). It is free from pesticides and does not contain any artificial sweeteners and preservatives.


  • 750 mg of CBD per bottle
  • 30 ml in a single container
  • Full-spectrum hemp extract
  • Third-party tested
  • Zero high


  • Gluten-free
  • Vegan-certified
  • No sweeteners
  • No artificial flavors
  • 100% natural


  • No flavor available 
Spruce is the perfect company for those who are looking to cure IBD. They offer high-quality full-spectrum products made from the finest hemp strains, which are backed by lab testing.

3: CBDPure: Hemp Oil – Variety of Strengths 

CBDPure: Hemp OilThe mission of CBDPure is to provide the best CBD products worldwide. All of their plants are grown without pesticides or herbicides. They aim to make it as organic and experience possible for all types of conditions, such as bowel infections.

The company is committed to ensuring that its customers know exactly what they are putting into their goods. Their website outlines the testing process for purity, which includes checking cannabinoid and terpene levels and solvents.

This brand does not have any artificial flavors or preservatives. That is why all of the products are minimally processed to be enjoyed with all organic ingredients. 

You get one natural flavor in three concentrations: 300, 600, and 900 mg in a 30 cc of the full-spectrum hemp oil bottle. In addition, CBDPure offers a 100% money-back guarantee to those not satisfied with the product.


  • Independent lab tested
  • 300 – 1000 mg potencies
  • CO2-based extraction
  • 60 servings per bottle
  • Full-spectrum hemp extract


  • No added artificial flavors
  • Preservative-free
  • No carrier oil used
  • US-raised hemp
  • Free from pesticides


  • No flavor options 
  • The website is not enough user-friendly
For people who have Crohn’s disease, this brand offers organically grown hemp at a reasonable rate. Pure CBD includes high-quality ingredients and has helped many individuals find relief for IBD conditions.

4: Joy Organics: CBD Tincture Collection – Wide Range of Flavors

 Joy Organics: CBD Tincture Collection Joy Organic’s brings this phytocannabinoid-infused hemp for the maximum entourage effect. This oil collection is made with a wide variety of 112 cannabinoids that include terpenes and flavonoids found in nature to provide relief from pain.

This brand extracts full-spectrum oil using CO2 extraction, which preserves all plants' natural goodness. These can be made from plants with high amounts of THC and CBD to create the perfect balance for your needs.

These CBD oils go through a rigorous testing process, and lab tests are shared with the user for utmost satisfaction. These assure that the quality is maintained at an appropriate level for consumers to enjoy these benefits.

These oils are made using only the finest U.S grown hemp, with higher standards than any other place. It is available in 450 and 900 mg concentrations with a diverse range of flavors, which are as follows:

  • Fresh Lime
  • Tranquil Mint
  • Orange Bliss
  • Summer Lemon
  • Unflavored
  • Tropical Sunrise

You can get it in both full- and broad-spectrum options as per your need. To make the oil more bioavailable, it goes through a process called nanotechnology.


  • USDA-certified formula
  • Rigorous third-party lab testing
  • 15 – 75 mg of CBD per serving available
  • Full-spectrum & broad-spectrum CBD
  • US-cultivated plant


  • No animal-based testing
  • Zero high
  • 90-day satisfaction assurance
  • Unique flavor options
  • Nanotechnology for high absorption rate


  • Expensive
  • No international delivery
Joy Organics shares the delight of providing its customer with both full and broad-spectrum CBD oils to deal with Chron’s pain. In addition, it is a gluten-free product, available in five different flavors.

5: Royal CBD: Full Spectrum CBD Oil – High Potent

 Royal CBD: Full Spectrum CBD Oil Royal CBD is a US-based company that sells organic hemp oil extractions on top of other formats like capsules and topical goods, using domestically grown hemp for extraction with CO2 supercritical fluid technology to maintain the high-quality standards from start-to-finish in every step.

Royal CBD Oil 2500 mg is the best choice for those who have Crohn's disease. The product contains all-natural ingredients that are chemical-gluten-free, and vegan, making it safe for everyone to use.

Royal CBD has strict quality control measures to ensure its products are safe, potent, and pure. Moreover, their products undergo third-party lab tests, so customers know what they are getting is entirely secure for consumption.

It is available in a 30 ml bottle with ultra-strength concentration to alleviate anxiety, depression, pain, IBD, and more symptoms. If you do not feel satisfied with the product, you can return it as it comes with a 30-day money-back guarantee. 


  • 2500 mg of CBD strength 
  • US-grown hemp extract
  • Lab verified
  • Full-spectrum hemp extract
  • CO2 sourcing method


  • 30-day money-back policy 
  • Gluten-free
  • Free from GMO
  • High strength 
  • No chemicals


  • Available online only 

Royal CBD offers a broad range of products, and the prices are affordable. This best-selling CBD oil for Crohn’s disease is known for providing relief from pain without causing discomfort.

Read Here: Royal CBD Brand and Products Review with Consumers Review

6: Gold Bee: Premium CBD Oil – 100% Vegan 

 Gold Bee: Premium CBD OilGold Bee has created the perfect CBD oil for Crohn’s disease. It is available in three flavors, with concentrations of up to 1200 mg of CBD per bottle with no more than 40 mg per serving. However, you can also get a 2400 mg formula for more potent and vegan-friendly results. 

The raw ingredients for these products come from organically grown hemp, which is extracted using CO2 to maintain the original chemical profile. The honey flavor in this oil comes from using California-grown plants to make the full-spectrum product more potent against inflammatory bowel disease.

This product is a great way to get that natural, honey-like flavor without unhealthy sugar or chemicals. The ingredients are high quality and do not cause any problems with your blood glucose level. It is a non-GMO product that undergoes third-party lab tests and comes with a return policy.


  • 1200 mg, 2400 mg CBD per bottle
  • 30 servings/bottle
  • Full-spectrum hemp extract
  • 3rd party lab certified
  • Made with American hemp


  • Non-GMO 
  • Unsweetened natural flavor
  • Instant results
  • Vegan
  • Entourage effect 


  • Not available in other hemp extracts
  • Relatively expensive
Gold Bee brings a delicious and all-inclusive product designed to help relieve the symptoms of IBD. It is an excellent choice for those who suffer from this disease or other debilitating conditions like Crohn’s.

7: CBDistillery: CBD Oil Tincture – Best for Medium Strength 

 CBDistillery: CBD Oil Tincture If you are looking for a company with the broadest selection of CBD formats, then CBDistillery is your best bet. This full-spectrum tincture is enough to deal with all the issues related to IBD and other conditions.

The company has two options to provide CBD products. The full spectrum option offers a variety of benefits, but it also varies in cost compared to the broad-spectrum version. However, those looking for high quality without spending too much money buying should go for this product.

These products are perfect for those who want an easy system without feeling too high. It does not have any traces or odors from THC, so that you can feel safe about the discreetness of this selection. You get 33 mg of CBD per serving in this 30 ml oil container.

CBDistillery’s oils are excellent for those who suffer from Chron's disease. In addition, they have the best affordable products, making them one of a kind.


  • Full-spectrum CBD oil
  • 1000 mg CBD per bottle
  • 33 mg of CBD each serving
  • Made in the USA
  • 30 ml oil container


  • COA available
  • Zero psychoactive 
  • THC-free
  • Sourced with CO2 practice
  • Non-addictive


  • No flavors 
CBDistillery brings an effective CBD formula to treat your condition instantly. It is undoubtedly another best choice for IBD patients. In addition, you may explore the website to learn about different hemp extracts.

The Common Symptoms of Crohn’s Disease 

The intestines are a complicated system of organs that perform many essential functions. They digest food, produce necessary bacterial populations for digestion and immunity protection in the body, and regulate your internal environment with chemicals.

Fanciful though it may sound to some people, IBD stands out from other inflammatory bowel diseases primarily because sometimes Crohn’s disease can lead to ulceration (tissue destruction) and cancerous growths called lymphomas.

Following are the common symptoms of Crohn’s:
🔴 Headaches
🔴 Fatigue
🔴 Harsh pain in the digestive tract
🔴 Weight loss or gain
🔴 Deep inflammation
🔴 Autoimmune symptoms
🔴 Diarrhea or constipation

There are many different kinds of inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, which can affect the quality of life for those who suffer from them.

Despite the theory that Crohn’s disease is incurable, treatments like CBD oil are available to ease its symptoms and allow patients to function normally.

The Benefits & Disadvantages for Crohn’s Disease 

Let’s look at a few pros and cons of the CBD for bowel diseases:

The Advantages: 

✔️ When CBD interacts with the ECS, it brings balance to your digestive tract.

✔️ One way this happens is by interactivity with receptors that are responsible for nausea and other stuff.

✔️ It negligibly affects the immune system, unlike other treatments that can have inflammatory effects and worsen symptoms in some patients with this condition.

✔️ CBD reduces abdominal pain and diarrhea, two common symptoms of IBD, as per research. 

✔️ CBD does not have the psychoactive properties of THC, making it safe for all ages.

The Disadvantages:

There has been limited research on how it can help with Crohn’s disease, especially in human clinical trials, and we need more data before saying for sure that CBD will work or not work at all.

Animal studies have been inconclusive regarding CBD’s efficacy for inflammatory bowel disease, or IBD.

The FDA, however, does not approve any health claims about cannabis products, and the agency remains skeptical that the plant will become a viable cure-all in modern society.

The market for CBD is largely unregulated, so the products you buy may not have been made by a company that has been appropriately vetted. In addition to safety concerns about pesticides and solvents residue in your product if produced cheaply overseas.

How Does CBD Oil Help with Crohn's Disease?

When inflammation is present, CBD and other cannabinoids are upregulated. When this occurs, their presence stimulates colitis more than usual because they heighten the condition for those with Crohn's disease or ulcerative.

The use of cannabinoids has been studied to help treat inflammation. However, when these drugs are blocked or taken out of our system, there is an increased risk that we will experience the opposite effect, which causes problems for those who need relief from pain.

The endocannabinoid system is deeply involved in regulating gut homeostasis, sensation, and movement throughout your body. It has been recently discovered to be a significant player in treating IBD.

A recent study has revealed that cannabinoids can reduce intestinal permeability and inflammation. Both of these play a role in IBD patients who experience flare-ups.

Wrapping Up:

Crohn's disease, an inflammatory bowel disorder, is a chronic condition that affects more than three million Americans. It can cause abdominal pain, malnutrition, severe diarrhea in infected individuals, and fatigue, resulting in weight loss or increased appetite for food.
CBD is the future of medicine. For example, it has shown promise in treating Crohn’s disease, which currently does not cure but can be managed effectively with natural remedies like CBD oil for pain relief and improved digestion, among other benefits.

Medterra has become the best CBD oil for Crohn’s disease and will give you your much-needed relief. Although there is no direct evidence to support CBD as a viable treatment for Crohn’s disease, some doctors and health experts are optimistic about the potential of this cannabinoid.

See More:

Top 7 Best CBD Oil for Colitis: Most Popular Brands for Relief

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