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  • Rebecca R. Lopez

More than 350 million people worldwide are affected by arthritis. Not only does it reduce the quality of life for individuals who suffer from this condition, but there is also an economic impact in terms of how much time off work they require to manage their symptoms.

People can take medications to reduce discomfort linked with arthritis, but there is also a growing trend towards using CBD as a potential source for much-needed comfort instead of pharmaceuticals which have side effects and long-term health risks involved.

Our top 10 list of favorite CBD brands is a great resource for finding the best CBD cream for arthritis pain. We checked these companies against our rating system, which takes time and research to create so that you do not have any trouble deciding on your next purchase.

Thorough List of Best CBD Cream for Arthritis Pain Reviews

  1. CBDfx: CBD Cream for Muscle & Joint – Overall Best
  2. Joy Organics: CBD Cream – Revitalizing Solution
  3. Royal CBD: CBD Cream (Cool Relief Balm) – High-Quality Formula
  4. Hemp Bombs: CBD Pain Freeze – Commendable for Pain Relief
  5. Charlotte’s Web: Hemp-Induced Cream with CBD– Full-Spectrum Recipe
  6. Receptra Naturals: Serious Relief – Anti-Inflammatory Formula
  7. Medterra: Pain Relief Cream – Best for Sustainability
  8. Kiara Naturals: CBD Muscle & Joint Salve — Must for Muscle Pain
  9. R+R Medicinals: CBD Cream – Free from Menthol
  10. Nuleaf Naturals: CBD Balm – Simplest Ingredients

1: CBDfx: CBD Cream for Muscle & Joint – Overall Best Treatment

CBDfx: CBD Cream for Muscle & Joint

CBDfx is the go-to brand for all your CBD needs. Their topicals are made with potent botanical ingredients that bring relief while nourishing the skin.

This potent joint cream’s soothing and cooling effects are quickly absorbed by your body to relieve pain and discomfort in the joints. It contains white willow bark extract with caffeine mixed together for an anti-inflammatory effect, along with menthol that soothes arthritis.

This broad-spectrum CBD is vegan and cruelty-free that gives a wholesome experience to people with arthritis and joint pain. It is lab tested and also comes with a 60-day guarantee for purity.


  • Broad-spectrum hemp extract
  • USA made
  • Lab-tested
  • Three potencies: 500 mg, 1000 mg, 1500 mg


  • Solvent-free
  • 60-day money-back guarantee
  • Non-detectable THC
  • Natural pain reliever
  • Cruelty-free


  • Only one formula available
CBDfx brings a series of CBD products to relieve your pain and give a soothing environment at inexpensive rates. This broad-spectrum formula is free from THC and gives a complete experience.

2: Joy Organics: CBD Cream – Revitalizing Solution

Joy Organics: CBD Cream

Joy Organics is here to help you live your best life possible. They offer premium CBD products that will work for more than just your skin, including creams and salves.

Is your body feeling sore after a workout? Are you in pain due to arthritis? This CBD cream will help soothe the pain and keep you moving forward. Its each 250 mg of CBD in each an ounce jar will revitalize your muscles and joints.

It is made with broad-spectrum hemp extract, promising zero THC. It Is made cruelty-free, goes under third-party lab testing, and also comes with free shipping for an unforgettable purchase.


  • Broad-spectrum CBD
  • 250 mg of CBD per container
  • US-farmed plant
  • 3rd party lab tested
  • Non-GMO


  • 30-day satisfaction guarantee
  • 0.0% THC
  • Free carbon-neutral shipping
  • Cruelty-free
  • Fast absorption


  • Only one concentration is available
The CBD cream by Joy Organics provides all-natural relief against pain. It has no THC and is farmed organically for dealing with issues like back pain and arthritis.

3: Royal CBD: CBD Cream (Cool Relief Balm) Royal CBD: CBD Cream (Cool Relief Balm)

There are many ways to soothe painful joints, but nothing like a cool gentle relief by Royal CBD. The ingredients in this product have been known for their inhibitory effect on pain pathways by blocking its transmission at its source through special receptors.

This CBD cream also contains arnica herbal extracts, which have been used for centuries to heal joint and muscle pain. This particular herb is perfect for promoting healing in arthritis.

This special formula contains a number of anti-inflammatory elements such as eucalyptus, sweet marjoram, roman chamomile, and CBD. A joint supplement with over a dozen ingredients, this formula fights pain and inflammation in the tissue of joints.

This product by Royal CBD is a 500 mg broad-spectrum hemp extract made from premium US-grown hemp. This product contains terpenes and flavonoids that work together in promoting wellness.


  • Broad-spectrum hemp extract
  • 500 mg of CBD per bottle
  • US-grown hemp
  • Independent lab testing
  • 3-oz jar


  • Gluten-free
  • Natural ingredients
  • 30-day money-back guarantee
  • Zero THC
  • Supportive cannabinoids, terpenes


  • Might feel greasy for an hour after applying
  • Expensive
If you prefer having a premium-quality formula for pain relief, Royal CBD is the perfect option. It is a great remedy for arthritic joints and gives an all-natural experience.

Read Here: The Royal CBD Brand Review of 2022 - The Goods and Bad

4: Hemp Bombs: CBD Pain Freeze – Commendable for Pain Relief

 Hemp Bombs: CBD Pain Freeze

The cooling effects of this CBD cream by Hemp Bombs are a great way to relieve arthritis pain in just minutes. The topical cream combines this with CBD isolate, making it easy for anyone who suffers from joints like rheumatoid arthritis and autoimmune disease sufferers to experience relief.

This CBD dose varies from 100 mg to 1000 mg of CBD. Its soothing traits are commendable to relieve your pain from discomfort. This CBD formula is ideal for easing the pain of common sources of skin and connective tissue pain such as sunburns, muscle strains, or sprains.

Hemp Bombs brings a line of CBD products that can be found worldwide because THC concentrations are nearly undetectable. Their customer reviews online show plenty of satisfied customers who enjoy using these rubs to help relieve pain and tension.


  • Three different strengths
  • CBD isolate
  • Independent lab testing
  • USA-grown hemp
  • 4% menthol


  • No THC
  • Active ingredients
  • Pure CBD extract
  • Bio-cooling gel


  • Not strong enough for severe pain
With its new freezing formula, Hemp Bombs has dropped a bomb in the market to bring a sense of calmness and relief to people with arthritis and joint pain. Its pure CBD extract gives nothing but satisfaction at affordable prices.

5: Charlotte’s Web: Arthritis Aches & Pain Relief Cream Charlotte’s Web: Arthritis Aches & Pain Relief Cream

Charlotte’s Web is a company that specializes in pain relief products for patients who have arthritis, joint discomfort, and other types of muscular soreness. They offer top-notch topical medications using ingredients commonly found within nature to provide relief.

The active components include beeswax and menthol, which work quickly but do not last too long, so you will need multiple applications throughout your day if necessary. Once you experience the relief from chronic pain, it is so much easier to live with.

This pain-relieving cream is optimized for fast temporary relief of arthritic symptoms. It contains ingredients like cotton oil seed and menthol, which provide the desired effect sooner than other products on the market.

The formula also includes inactive THC-free CBD hemp oil mixed with other natural moisturizers such as jojoba seed oil, all while being safe enough to use on sensitive skin without any side effects or irritations.


  • 200 mg CBD extract per bottle
  • US Hemp Certified Authority 
  • Third-party lab testing
  • 4% Menthol
  • 48 g/bottle


  • THC-free
  • Gluten-free
  • Vegan-friendly
  • Paraben-free
  • No artificial dyes 


  • Shipment delay feedback from customers 
Charlotte’s Web is a reputable name in the CBD market. It brings affordable products with full-spectrum hemp extract that promise regulated THC that provides pain relief. It is another best CBD cream for arthritis pain and other joint discomforts.

6: Receptra Naturals: Serious Relief – Anti-Inflammatory Formula

Receptra Naturals: Serious Relief

Receptra Naturals provides a variety of CBD topical products to help relieve pain in the body. The lotions, salves, and balms feel good on your skin while providing relief for long-term inflammation from ailments such as arthritis or back injury.

This brand offers products with additional ingredients, including Arnica and camphor, to soothe dry skin. The jojoba oil helps absorb the pain of minor injuries while also soothing it with its healing properties for quick relief from irritation-causing issues such as bruising or swelling.

This CBD topical absorbs quickly and deeply, providing relief for irritated areas. The organic ingredients blend provides fast recovery with their natural inflammation-reducing traits, making moving past sore muscles or joints easier while also protecting you from everyday stressors.


  • Full-spectrum hemp extract
  • 800 mg of CBD per jar
  • 70g Hemp balm
  • Made in USA


  • 30-day money-back guarantee
  • Organic vitamin E
  • Natural plant extract
  • High absorption rate
  • Award-winning formula


  • Not cheap
Receptra Naturals’ CBD cream is the best anti-inflammatory product you will find on the market. It is rich in vitamins and comes with a high absorption rate for an overall laudable experience.

7: Medterra: Pain Relief Cream – Best for Sustainability

Medterra: Pain Relief Cream 

Medterra is a company that produces top-of-the-line CBD-infused products. Medicated with modern ingredients, their cream can easily reach the outer layers of skin and will not have any plasticizing or synthetic chemicals which may irritate your sensitive area.

Mediterra’s CBD cream is designed for those who want an all-natural way to help treat themselves without having side effects from harsh medications or supplements.

The soothing effect of this pain relief cream is known as an over-the-counter remedy for arthritis pain. It blends menthol with jojoba oil to deliver a fast-acting, rapid response to all types of discomfort experienced by users.


  • USA-grown hemp
  • 500 mg, 1000 mg CBD strengths
  • Laboratory tested
  • U.S. Hemp Authority
  • CBD isolate


  • Free from THC
  • Non-GMO
  • No Pesticides
  • Active ingredients
  • 30-day money-back guarantee


  • Customer service not available on Sunday
Medterra offers CBD isolate CBD cream to shoo away your arthritic pain along with other muscle and joint pains. Order from this brand to get purity and safety at affordable prices.

Recommended Read: Best CBD Cream for Plantar Fasciitis

8: Kiara Naturals: CBD Muscle & Joint Salve — Must for Muscle Pain Kiara Naturals: CBD Muscle & Joint Salve

For those looking to find the perfect balance of CBD and organic herbs in their product, Kiara Naturals is your go-to brand. They ship all around Europe, including the US and throughout North America, emphasizing high-grade ingredients paired with some profound benefits.

This company is here to help you manage your aches and pains. The topical pain cream helps reduce muscle soreness, stiffness, or inflammation by applying heat to be absorbed more effectively into the skin cells.

This CBD salve has full-spectrum hemp extract, which offers pain-killing and anti-inflammatory benefits. It also contains ingredients like Arnica, common rue, camphor menthol, and more for a complete experience. It is amazing how this cream can help with both rheumatoid arthritis and osteoarthritis.


  • 1000 mg of CBD
  • Full-spectrum hemp extract
  • Organic Swiss hemp
  • 50ml per container
  • 3rd party lab tested


  • 60-day money-back guarantee
  • THC-controlled formula
  • All-natural ingredients
  • 30% arnica
  • GMP


  • Lack of strengths and flavors
Kiara Naturals is another best CBD cream for arthritis pain on the list that will relieve your pain in no time. It is an easy-to-use formula that will provide nothing but satisfaction against arthritis.

9: R+R Medicinals: CBD Cream – Free from Menthol
 R+R Medicinals: CBD Cream

R+R Medicinals’ CBD Cream is an excellent pain relief cream that contains 1000 mg of cannabidiol for those who have arthritis or other causes. It is free of fragrances, dyes, menthol, so you will not experience any side effects.

This cream is made of all-natural ingredients, like MSM and Arnica. It is perfect for sensitive skin or allergies, and it even includes medicinal plants. The 4 mg CBD content will provide potent relief from minor aches and pains.

You get 1000 mg of full-spectrum CBD in a single container. It is easy to apply with a high absorption rate. Moreover, it is vegan and comes with third-party lab results. You also get a 30-day money-back guarantee if you are not satisfied with it.


  • Full-spectrum CBD
  • 1000 mg of CBD per container
  • Third-party lab testing
  • 2.5 FL Oz
  • 4 mg of minor cannabinoids


  • Menthol-free
  • No dyes
  • Free from artificial fragrances
  • Additional ingredients
  • Vegan


  • No strength options
R+R Medicinals’ CBD cream is perfect for those who are sensitive to traditional pain, and it provides a strong dose without menthol or dyes.

10: Nuleaf Naturals: CBD Balm – Simplest Ingredients
Nuleaf Naturals: CBD Balm

NuLeaf Naturals is a company that specializes in CBD products from organically-grown Colorado hemp. They have introduced their newest product, the CBD balm. This potent balm provides simplicity and effectiveness with an easy application for those looking into natural remedies.

This brand offers a full-spectrum CBD balm which is a dependable remedy for your skin’s needs. It contains just two ingredients: concentrated full-spectrum hemp extract and organic shea butter, available in strengths of 300 mg, 600 mg, or 900mg to cover large sections of the body.

It is sourced using the CO2 extraction method to procure cannabinoids for a full natural experience. It is made with organic hemp and goes through independent lab testing to ensure purity and safety.


  • Full-spectrum hemp extract
  • 300 mg, 600 mg, 900 mg strengths
  • Organic shea butter
  • Colorado-grown hemp
  • 0.5 oz, 1.0 oz, 1.5 oz


  • CO2 extraction process
  • 3rd party lab testing
  • Unscented
  • Full of cannabinoids
  • Natural ingredients


  • Relatively expensive
The CBD balm by Nuleaf Naturals is an excellent choice for those with sensitive skin or allergies because it absorbs quickly, relieving discomfort in joints and muscles while also moisturizing your skin. We suggest the 900 mg strength if you are suffering from arthritis pain.

The Safety & Side Effects of CBD Cream

The idea of using CBD cream can be appealing because the research shows it is safe to use without any negative side effects. Just apply and reapply as required but ensure topicals are applied over the skin, not ingested orally or smoked for medicinal purposes.

If you want to try CBD for yourself or your pet, there are a variety of products available. Some people choose edibles that offer the benefits in an easy-to-administer form; others go with tinctures, which can help pets get maximum relief from chronic pain as well.

If you have been experiencing dry skin or irritation due to an open wound, CBD cream may be the perfect fix. However, these situations must be healed before applying them. Otherwise, it could further irritate your sensitive areas and slow down natural healing.

Though CBD is generally considered safe, some people report feeling drowsiness and discomfort. However, when using a topical product like cream, there are few if any side effects that can be attributed to its usage. Therefore, consult a doctor before using it.


CBD is an effective treatment for pain because it actively fights the underlying causes of your discomfort while simultaneously muting transmission from sending pain signals to the brain. After applying the product, you will notice that its active ingredients start absorbing into your skin within minutes.

Be sure to choose a topical product from trustworthy CBD brands if you want the most out of your money. There are plenty on the market that contain trace amounts but advertise themselves as pain remedies when they are not anything close to it.

CBDfx offers the best CBD cream for arthritis pain and comes off as a complete package for other issues too. However, do a little bit of research on the brand before buying their product, starting with the list.


1: How quickly does CBD Cream work for pain?

CBD cream is a great option for those who need quick relief. Most customers report that the product worked within 15 minutes and gave them immediate results with cooling effects after application.

2: How does CBD cream work for arthritis?

Topical CBD cream is absorbed through your skin, and the soothing relief it provides can help with aches, pains, cramps. The menthol in topically applied cannabis will have an anti-inflammatory effect that reduces arthritic pain too.

3: How often should I use CBD cream?

We recommend using CBD cream up to four times a day. Apply it as often or infrequently you need depending on the level of discomfort you are experiencing with each application being 30 minutes apart.

4: Is CBD cream legal?

Yes, the CBD cream contains less than 0.3% THC, making it legal with both state and federal regulations.

5: How to apply CBD cream?

To get started, all that’s required is spreading some CBD cream over the affected area(s). This formula may be used on affected spots at one time or applied liberally throughout the entire body for pain relief.

See More:

Best CBD Oil for Joint Pain - Reliable Solutions 
9 Best CBD Creams for Eczema: Top Solutions for Skin Health

Best CBD Oils for Shingles Pain

Best CBD Cream for Neuropathy Pain - Top Picks

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